MPEG with different molecular weights after carboxylated was occurred esterification reaction to the hydroxyl groups at C-3 on the chitosan backbone, and the comb-shaped methoxy poly ( ethylene glycol) grafted chitosan ( CS-g-mPEG) which can be dispersed in water was prepared. 将不同分子量的mPEG的羟基羧化后,与壳聚糖分子链上3位羟基发生酯化反应,制备出梳形可分散于水的甲氧基聚乙二醇接枝壳聚糖(CS-g-mPEG)。
Firstly, water solubility of the chitosan was improved by methoxy poly ( ethylene glycol)( mPEG) in this paper. 本论文首先利用甲氧基聚乙二醇(mPEG)改善壳聚糖的水溶性。